Injectables
Injection Vipcef
Composition:
Each vial contains:
- Ceftriaxone (as Ceftriaxone Sodium) 1000 mg
About:
Ceftriaxone 1000 mg Injection is a broad-spectrum antibiotic used for the treatment of a wide range of bacterial infections. It belongs to the cephalosporin class of antibiotics, which works by inhibiting the bacterial cell wall synthesis. This results in the death of the bacteria, making it effective against both Gram-positive and Gram-negative bacteria.
Composition & Purpose:
Ceftriaxone 1000 mg contains Ceftriaxone sodium as the active ingredient. It is designed for parenteral administration (injection or infusion) to treat serious infections caused by susceptible microorganisms. It is often used in hospital settings for critical infections, including respiratory, urinary, and blood infections.
Key Features:
- Broad-spectrum antibiotic: Effective against a wide variety of bacteria.
- Single-dose efficacy: Provides effective treatment with a single dose of 1000 mg.
- Well-tolerated: Commonly used in both adult and pediatric patients.
- Convenient administration: Can be given intravenously or intramuscularly.
- High bioavailability: Quickly enters the bloodstream after injection.
Indications:
Ceftriaxone 1000 mg Injection is indicated for the treatment of bacterial infections caused by susceptible organisms, including:
- Lower respiratory tract infections (e.g., pneumonia)
- Urinary tract infections
- Meningitis
- Bacterial septicemia
- Skin and soft tissue infections
- Intra-abdominal infections (e.g., peritonitis)
- Bone and joint infections
- Gonorrhea
- Prophylaxis in surgical procedures
Dose:
The dosage of Ceftriaxone 1000 mg Injection depends on the type and severity of the infection:
- Adult Dose: 1000 mg to 2000 mg once daily (administered intravenously or intramuscularly)
- Pediatric Dose: 50 mg/kg once daily (up to 100 mg/kg if needed in severe infections)
- Severe infections: Dosage may be adjusted based on the clinical condition of the patient.
- Duration: Typically 5-14 days depending on the infection.
Side Effects:
Common side effects include:
- Nausea, vomiting, and diarrhea
- Rash or allergic reactions (such as itching or swelling)
- Pain at the injection site
- Elevation of liver enzymes
- Headache or dizziness
- Injection site reactions
- Rarely, anaphylaxis or severe allergic reactions
Consult a healthcare provider for advice if side effects persist.
Precautions:
- Allergy: Do not use if allergic to Ceftriaxone or other cephalosporins.
- Pregnancy: Use only if clearly needed, as Ceftriaxone may pass into breast milk.
- Renal or hepatic impairment: Dose adjustments may be required in patients with renal or liver dysfunction.
- Interaction with other medications: Inform your doctor if you are taking any anticoagulants, diuretics, or other antibiotics.
- Superinfection: Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.
Storage Instructions:
- Store at room temperature (15°C – 25°C) away from moisture and heat.
- Do not freeze.
- Keep out of reach of children.
- After reconstitution, use the solution immediately or store as per the manufacturer’s guidelines (usually 24-48 hours depending on the storage conditions).
Injection Vipcef-SB
Composition:
- Ceftriaxone (1000 mg)
- Sulbactam (500 mg)
About: Ceftriaxone is a broad-spectrum cephalosporin antibiotic that is used to treat a wide variety of bacterial infections. Sulbactam is a beta-lactamase inhibitor that enhances the effectiveness of ceftriaxone by preventing the breakdown of the antibiotic by bacterial enzymes. Together, these two components provide powerful antibacterial activity against a wide range of infections.
Composition & Purpose:
- Ceftriaxone (1000 mg): A third-generation cephalosporin that is effective against both Gram-positive and Gram-negative bacteria. It works by inhibiting bacterial cell wall synthesis, leading to bacterial death.
- Sulbactam (500 mg): A beta-lactamase inhibitor that protects ceftriaxone from being inactivated by beta-lactamase enzymes produced by bacteria. This combination ensures extended antibacterial action against resistant strains.
Key Features:
- Effective Combination: Ceftriaxone + Sulbactam offers a broad spectrum of antibacterial activity.
- Convenient Dosage: Available in an easy-to-administer injectable form.
- Enhanced Efficacy: The inclusion of Sulbactam extends the range of action against beta-lactamase-producing bacteria.
Indications:
- Respiratory Tract Infections: Including pneumonia, bronchitis, and sinusitis.
- Urinary Tract Infections: Such as pyelonephritis and cystitis.
- Skin and Soft Tissue Infections: Including cellulitis, abscesses, and wound infections.
- Intra-abdominal Infections: Such as peritonitis and cholecystitis.
- Bone and Joint Infections: Including osteomyelitis and septic arthritis.
- Meningitis: Ceftriaxone is effective in treating bacterial meningitis.
- Septicemia: Treatment of bloodstream infections caused by susceptible organisms.
Dose:
- Adults: 1–2 g of Ceftriaxone and 500 mg of Sulbactam, administered once or twice daily depending on the severity of the infection.
- Pediatric Patients: The dose depends on the child’s weight and age. Consult a pediatrician for the appropriate dosage.
Side Effects:
- Common side effects may include nausea, vomiting, diarrhea, or rash.
- Allergic reactions such as itching, swelling, and difficulty breathing may occur.
- Local irritation or pain at the injection site.
- Changes in liver function tests or kidney function.
- In rare cases, severe side effects such as anaphylaxis or blood disorders may occur.
Precautions:
- Allergy: Caution should be taken in patients with a history of hypersensitivity to cephalosporins or penicillin.
- Pregnancy and Breastfeeding: Use only if clearly needed and under medical supervision.
- Renal Impairment: Dose adjustment may be required in patients with kidney problems.
- Liver Impairment: Caution is advised in patients with liver disease.
- Drug Interactions: May interact with other antibiotics or blood thinners, so a doctor should be consulted before use.
Storage Instructions:
- Store in a cool, dry place at room temperature (15°C to 25°C).
- Keep the vial tightly closed and away from light.
- Do not freeze the injectable form.
- Keep out of reach of children.
Injection Cefokra-S
Composition:
- Cefoperazone 1000 mg
- Sulbactam 500 mg
About:
Cefokra-S is a combination of Cefoperazone, a third-generation cephalosporin antibiotic, and Sulbactam, a beta-lactamase inhibitor. This combination is used to treat a wide range of bacterial infections by enhancing the activity of Cefoperazone against beta-lactamase producing organisms. It is effective against both Gram-positive and Gram-negative bacteria.
Purpose:
The combination is used to treat severe infections caused by susceptible bacteria. It works by inhibiting bacterial cell wall synthesis and preventing bacteria from breaking down the antibiotic, thereby increasing its effectiveness.
Key Features:
- Broad-spectrum antibiotic
- Combats a wide range of bacterial infections
- Combines the power of Cefoperazone and Sulbactam
- Suitable for patients with infections resistant to other antibiotics
- Administered via intravenous or intramuscular injection
- Helps prevent bacterial resistance
Indications:
- Respiratory tract infections (pneumonia, bronchitis)
- Urinary tract infections (UTI)
- Soft tissue infections
- Bone and joint infections
- Intra-abdominal infections (peritonitis)
- Septicemia
- Gynecological infections (pelvic inflammatory disease)
- Meningitis (in some cases)
Dose:
- Adult Dose:
The usual dose is 1 g of Cefoperazone and 0.5 g of Sulbactam every 12 hours or as prescribed by the healthcare provider. - Pediatric Dose:
Dosage should be determined by a pediatrician based on the child’s weight and age.
Side Effects:
- Common side effects may include:
- Diarrhea
- Nausea and vomiting
- Rash
- Injection site pain or irritation
- Fever
- Serious side effects may include:
- Allergic reactions (swelling, hives, difficulty breathing)
- Liver dysfunction (yellowing of the skin/eyes)
- Blood disorders (low white blood cells or platelets)
- Seizures (rare)
Precautions:
- Allergy: Avoid in patients with a history of hypersensitivity to cephalosporins or penicillins.
- Pregnancy & Lactation: Use during pregnancy only if clearly needed, as it passes into breast milk.
- Kidney/Liver Disease: Use with caution in patients with impaired kidney or liver function.
- Drug Interactions: May interact with other drugs, including blood thinners (e.g., warfarin) and other antibiotics.
- Superinfection: Prolonged use may lead to superinfection (e.g., yeast infections).
Storage Instructions:
- Store at room temperature, away from heat and moisture.
- Keep in a dry place, out of the reach of children.
- Protect from direct sunlight.
- Do not use after the expiry date printed on the packaging.
Injection Panlot
Composition
- Pantoprazole Sodium (Equivalent to Pantoprazole) – 40 mg
- Excipients – Sodium Carbonate, Water for Injection, Sodium Chloride, etc.
Purpose
Pantoprazole 40 mg Injection is designed to provide effective control over conditions related to excess stomach acid production, including peptic ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. It is mainly used when oral administration is not feasible or in severe cases requiring intravenous therapy.
Key Features
- Fast-acting relief from acid-related conditions.
- Reduces stomach acid production, promoting faster healing of ulcers and esophageal tissues.
- Suitable for intravenous administration in hospital settings.
- Helps prevent complications in patients who cannot take oral medications.
Indications
Pantoprazole 40 mg Injection is indicated for:
- Gastroesophageal reflux disease (GERD) with esophagitis.
- Peptic ulcers and duodenal ulcers.
- Zollinger-Ellison syndrome (a condition involving excessive acid secretion).
- Short-term treatment of severe acid-related conditions when oral therapy is not possible.
- Prevention of upper gastrointestinal bleeding due to stress ulcers in critically ill patients.
Dose
- Adult Dose: Typically, 40 mg once daily, administered intravenously, depending on the severity of the condition.
- The dose may be adjusted based on the patient’s condition and response to therapy.
- Duration of treatment varies based on the specific indication.
Side Effects
- Common: Headache, dizziness, nausea, abdominal pain, diarrhea, or constipation.
- Rare: Allergic reactions, severe skin reactions, muscle cramps, or blurred vision.
- Long-term use may increase the risk of fractures, vitamin B12 deficiency, and Clostridium difficile infection.
Precautions
- Hypersensitivity: Avoid use if there is a known allergy to pantoprazole or any other PPIs.
- Liver Function: Use with caution in patients with liver impairment.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.
- Bone Health: Long-term use may affect bone density, leading to a higher risk of fractures.
- Drug Interactions: May interact with certain medications like warfarin, methotrexate, or other PPIs.
Storage Instructions
- Store at room temperature (20-25°C or 68-77°F).
- Protect from light and moisture.
- Keep out of reach of children.
- Do not use after the expiry date printed on the label.
Injection Diclomy-AQ
Composition:
- Active Ingredients:
- Diclofenac Sodium: 75 mg
- Benzyl Alcohol: 4% w/v
About: Diclofenac 75 mg & Benzyl Alcohol 4% w/v Injection is a combination medication that provides effective relief from pain and inflammation.
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, which are chemicals responsible for causing inflammation, pain, and fever. Benzyl Alcohol acts as a preservative and solvent to maintain the stability of the injection. This formulation is used for the treatment of moderate to severe pain in various conditions.
Composition & Purpose:
- Diclofenac Sodium (75 mg): A potent anti-inflammatory and analgesic agent used to reduce pain, swelling, and stiffness in conditions like arthritis and injuries.
- Benzyl Alcohol (4% w/v): A preservative and stabilizer for the injection, preventing contamination and ensuring the effectiveness of the medication.
Key Features:
- Provides fast and effective pain relief.
- Reduces inflammation and swelling.
- Suitable for moderate to severe pain management.
- Contains Benzyl Alcohol as a preservative to ensure stability.
Indications:
- Acute pain management (e.g., post-operative pain, pain due to injuries or trauma).
- Chronic inflammatory conditions like osteoarthritis and rheumatoid arthritis.
- Musculoskeletal pain and soft tissue inflammation.
- Conditions requiring potent anti-inflammatory action.
Dose:
- The recommended dose for adults is 1 injection (75 mg of Diclofenac Sodium) administered intramuscularly once or twice a day, depending on the severity of the pain and doctor’s prescription.
- It is advised not to exceed the prescribed dose to avoid potential side effects.
Side Effects:
- Common side effects may include nausea, headache, dizziness, or injection site reactions (pain, redness, swelling).
- Gastrointestinal discomfort such as stomach ulcers, heartburn, or indigestion.
- Allergic reactions like rash, itching, or swelling.
- In rare cases, it can cause kidney or liver issues.
- Prolonged use can increase the risk of cardiovascular events like heart attack or stroke.
Precautions:
- Do not use this injection in patients with a history of hypersensitivity to Diclofenac or Benzyl Alcohol.
- Caution is advised for patients with a history of gastrointestinal disorders, such as peptic ulcers or bleeding.
- Avoid in patients with severe liver or kidney impairment.
- Not recommended during pregnancy (especially in the third trimester) or breastfeeding unless prescribed by a doctor.
- Patients with cardiovascular disease or hypertension should use this medication with caution.
Storage Instructions:
- Store in a cool, dry place away from direct sunlight.
- Keep the injection at room temperature (15°C to 30°C).
- Do not freeze.
- Keep out of reach of children.
- Ensure that the vial is tightly closed and stored according to the manufacturer’s guidelines.
